GRAIL

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.

Menlo Park, CA, USA

Hybrid

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Jobs//Hybrid//Peninsula//Data + Analytics//

Staff Statistical Analyst # 3740

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Employer Provided Salary: 154,000-204,000 Annually

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit www.grail.com.

The Staff Statistical Analyst contributes to the analysis of clinical study data through their statistical programming expertise. This individual will develop programs for and maintain complete and auditable documentation of the analysis of GRAIL’s clinical studies.

This is a hybrid role requiring 2 days on site in Menlo Park, CA

Responsibilities

Provide statistical programming support to pre-specified and exploratory analysis, formal reports, publications, presentations, and new statistical methodologies
Work closely with biostatisticians to review the statistical analysis plan (SAP), and create data and analysis program specifications based on the SAP
Maintain complete and auditable programming documentation for analysis of clinical studies
Contribute to the development, documentation and maintenance of a reusable programming code library
Serve as a member of clinical study teams
Work with data scientists closely on machine learning projects, as applicable
Work on engineering-oriented projects like dashboarding, automation, and scaling up efforts with large-scale genomic data, as applicable
May act as a biostatistician on small-scale projects
Stay abreast of industry developments in the Statistical Programming field and apply to appropriate systems and processes

Preferred Qualifications

B.S. or M.S in Statistics or related field or equivalent
5+ years statistical programming experience in academia or industry. Molecular diagnostics industry experience preferred.
Proficient in R or Python
Experience programming in SAS
Knowledge of applicable regulatory rules and guidelines, e.g., ICH, GCP, HIPAA
Experience with vcf, CDISC, SDTM, and ADaM compliant data sets is strongly desirable
Experience with regulatory submissions is strongly desirable
Ability to work independently on multiple concurrent projects in a fast-paced environment
Strong team player with demonstrated track record of success in cross-functional team environment

Desired experience

Molecular diagnostics industry experience preferred
R is strongly preferred
Regulatory filing experience is strongly preferred

The estimated, full-time, annual base pay scale for this position is $154,000 - $204,000. Actual base pay will consider skills, experience, and location.

Based on the role, colleagues may be eligible to participate in an annual bonus plan tied to company and individual performance, or an incentive plan. We also offer a long-term incentive plan to align company and colleague success over time.

In addition, GRAIL offers a progressive benefit package, including flexible time-off, a 401k with a company match, and alongside our medical, dental, vision plans, carefully selected mindfulness offerings.

GRAIL is an Equal Employment Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. GRAIL maintains a drug-free workplace.

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Joerg Bredno

Principal Scientist, Computational Biology and Interpretation

WIDEN YOUR SCOPE

A huge data set with an even bigger impact

“Cancer is a nasty, diverse disease that can affect widely different regions in the genome,” Principal Scientist Joerg Bredno said, and understanding how and why cells change isn’t easy. Luckily, his team works with more than 12 petabytes of molecular data — which translates to more than 1 million gigabytes — and a high-performance scientific computing environment that can handle analysis at that scale. With these tools, Bredno’s team is building an even larger training data set for the next generation of GRAIL’s early detection, multi-cancer screening test, slated to roll out this year.

It is rewarding that we can see, learn and share relevant insights from our data that so far doesn't exist anywhere else in the world in this form.

Ting Ma

Associate Director, Data Engineering

ACCELERATE TOGETHER

A team united by passion, fueled by collaboration

GRAIL’s team sets lofty goals for its products, which require the unique talents and perspectives of every employee. Take one eight-month study that Associate Director Ting Ma worked on, parsing data from a GRAIL-sponsored clinical trial. Due to the volume of data, teamwork was imperative to define and implement clinical features, refine codes with robust test cases and tweak them as continuous feedback rolled in. The work is important, but that's not the only plus: “Cross-functional team collaboration is fun,” Ma said. “You get to learn so much while contributing to each project.”

GRAIL is taking on a challenge that is unprecedented. It can only become successful when people with different expertise collaborate deeply.

Ying Luan

Associate Biostatistical Director

UNCOVER NEW OPPORTUNITIES

Sharp talent, perpetually looking to learn more

There’s a reason top talent, like Associate Biostatistical Director Ying Luan, joins GRAIL. “Here, I knew I could have the opportunity to contribute to the development of innovative analysis methodologies,” Luan said. She’s now working on a diagnostic aid project, planning and designing validation for clinical studies. It’s a new area for her, but there’s plenty of support for learning new skills at the company: With resources like LinkedIn Learning, workshops and conferences, she finds footing in the field, while diversity and inclusion trainings connect her fully to GRAIL’s culture.

Post-launch activities and payer’s reimbursement were new to me when I joined GRAIL. But now, I’m learning new things on a daily basis with different stakeholders in mind.

What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Culture

Volunteer in local community

Partners with nonprofits

Intermountain Healthcare

Open door policy

OKR operational model

Team based strategic planning

Open office floor plan

Employee resource groups

Employee-led culture committees

Hybrid work model

In-person all-hands meetings