Top Illinois Artificial Intelligence Startups (143)
At Quantum Rise, we're transforming how businesses use AI and automation to fuel growth and innovation. As an AI-native company, we combine human expertise with cutting-edge technology to solve real-world challenges. Our team is passionate about building products that are always on, continuously improving, and designed to help companies get the most out of their existing technology. But it’s not...
Prolaio is a clinical intelligence company dedicated to unlocking continuous, predictive and shareable heart data to liberate patients from hospital-based reactive care and accelerate every new therapy. The company was created by cardiologists, cardiovascular practitioners, and data scientists specifically to address the world’s number one cause of death — cardiovascular disease. By combining scientific rigor with cutting‑edge technology, Prolaio aims...
Bellagent is an enterprise-level AI agent platform built to automate everyday business operations with zero-touch integrations that connect instantly to more than 1,300 applications. Launched in 2025 by Proactifi Inc., and headquartered in Chicago, the platform is built for practicality with industry-leading compliance and security standards, enabling organizations to deploy AI agents without friction from day one. Bellagent’s mission to...
It’s an exciting time to be a Teragonian! Come help us transform the Private Equity industry and drive AI innovation while taking on new challenges and career growth opportunity. Teragonia provides an AI-based Value Orchestration platform for private equity backed mid-market operators, helping them transform fragmented operational data into an execution-focused view of business performance. With Teragonia, mid-market leaders align their...
Recognized by Crain’s as one of 2025’s Most Innovative Companies, UncommonX helps customers move from reactive defense to proactive resilience, with the context, prioritization, and insights needed to reduce risk and respond with precision. We believe cybersecurity should deliver more than alerts — it should deliver clarity, confidence, and control. That’s why we built an AI-powered Exposure Management platform that gives...
Who We Are Founded in 2001, Adage Technologies is a digital engineering firm building modern, AI‑enabled solutions that help organizations engage their audiences and operate more efficiently. With offices in Chicago and Medellín, our 120‑person team blends strategy, design, engineering, and data to create impactful digital experiences for performing arts organizations, associations and accreditation bodies, and manufacturing and distribution companies. What We...
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Bectran is an industry-leading SaaS platform which has grown rapidly to become the companion toolkit for the Credit Department just as a CRM is for the Sales Department. Recognized as a top innovator in the credit software industry, Bectran has been described by credit professionals as "the future of the credit department."
Prosodica transforms the way organizations understand and improve human connection. Our AI-powered conversation analytics platform captures every nuance of human dialogue—tone, pacing, empathy, and engagement—and translates it into measurable data that leaders can act on. By quantifying what was once intangible, Prosodica helps enterprises build stronger teams, elevate customer experiences, and create workplaces where communication drives results. At the heart of...
Caxy is a Chicago based software consulting and custom software development agency founded in 1999. Ranked top 3 software companies in Chicago by Clutch. Our secret sauce is that we want to make life as a developer fun, rewarding and not a grind. We have a commitment we call "The Caxy Promise." Many jobs in software are characterized by clients...
Flatfile, the pioneer of AI-assisted data exchange, provides companies and their software development teams with the easiest, fastest, and safest way to build the ideal data file import experience for their users. Hundreds of companies such as AstraZeneca, Square or Sage rely on Flatfile’s extensible, API-first platform to create enterprise-scale, intelligent, file-based data import solutions, increase developer productivity, reduce cost...
MSPbots is the market leader in proactive intelligence solutions for MSPs. Providing customized BI widgets, dashboards, and innovative apps to streamline daily responsibilities. With our solutions, we generate trackable metrics, send instant messages with issue explanations and resolution steps, and escalate recurring issues to managers for immediate action. MSPbots is dedicated to providing data-driven process automation to enable the growth...
We empower patients with secure custody and control of their health data and simplify navigating care. We connect patients with rare and chronic conditions to non-profit communities for support and they can opt-in to sharing confidential insights for research and development, and receive compensation for their contributions. Our healthcare ecosystem is where patients are active participants, care is personalized and...
HOPPR is building the first multimodal AI foundation model for medical imaging - founded by Khan Siddiqui, (CEO - founder of higi) and Oliver Chen (COO - founder of ilumihealth, acquired by Fosun Pharma) to accelerate AI application development and fine-tuning of AI models. Its deep learning platform is based on a proprietary privacy-compliant trust architecture that brings together data...
AI-powered content creation and reliable survey research in a single loop—smarter with every cycle. We help our customers win by turning voter feedback into more effective content and sharper strategy, faster and more reliably than ever before.
Qumis is generative AI built for the hardest part of insurance: understanding the policy. Built by attorneys. Made for scale. Used by the people who make insurance work.
Benmore Technologies is a Chicago-based software consulting and development firm that partners with founders, startups, and SMBs to design, build, and launch custom software products. We specialize in zero-to-one development, helping clients go from idea to MVP through a structured discovery process, clear technical architecture, and hands-on implementation. Our team works across web, mobile, AI/LLM, and cloud systems, using modern stacks...
Silkline is the platform that top hardware buying organizations use to seamlessly: 1. Collaborate with suppliers 2. Track requests, RFQs, quotes, orders, and more 3. Monitor team and vendor performance We centralize activity across your suppliers, provide real-time status updates, and integrate cleanly into your existing stack—no supplier onboarding required.
Basis Global is an award-winning insight consultancy that combines two decades of expertise with cutting-edge AI to help brands lead in a constantly changing world. With operations across the U.K. and U.S., our work spans over 60 countries and multiple sectors—including Consumer, B2B, and Health. By blending human creativity with AI precision, we deliver tailored strategies, actionable insights, and measurable...
At Lextech, we believe every employee has a right to Thrive At Work. We exist to help your employees unleash their individual brilliance. We help some of the world’s most admired companies end enterprise workflow chaos. We solve challenging business problems by applying technology to help employees thrive. With Lextech, an incremental human-centered approach to investing in your workforce produces tools that...
